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Forthcoming
Jayne M. "Multilinguality and Bilingualism in Education: The Kenyan Experience .". In: Kiswahili and Globalisation. University of Dar es Salaam; Forthcoming.
Jayne M. "Adult Literacy and the Place of Kiswahili.". In: proceedings on Language Curriculum Development. Kenyatta University; Forthcoming.
Jayne M. "Languages and Society: A Gender Perspective.". In: Proceedings of Understanding Gender Inequalities. Egerton University; Forthcoming.
R M, L.K O, J.O M, V M. "Cytotoxicity of principles from Bridelia micrantha.". Forthcoming.
Jayne M. A Dictionary and a Story Book. Nairobi: Nairobi Journal of Literature.; Forthcoming.
Submitted
JP E, S E, J K, LW I. "Biology of the coconut bug Pseudotheraptus wayi on French Beans. ." Journal of Insect Science . Submitted.
Jani PG, Gill H, Kotecha V. "Difficult Gallbladder Surgery, Improving Patient Outcomes Through Appropriate Surgical Decisions." East and Central African Journal of Surgery. Submitted;17(1).
Mbuge DO, MM K, E BKM, S M, DA M, J A. "The Effect of Drying Temperature on Nutrient levels in Oyster Mushroom." AJST. Submitted.
Janet Muhalia Chumba, Andanje Mwisukha RMK. "Extent of public support for physical education in Kenya." International Journal of Business and Social Science. Submitted;4(10). Abstract

Abstract The mass media have a fundamental role to play in the development of Sports.
Their contribution towards uplifting performance and popularizing sports is particularly
critical in the developing countries where sports programmes tend to receive minimal
attention and resource allocation. The mass media are important tools for marketing,
publicizing and popularizing sports. Their specific roles include bringing talent into the
limelight, giving recognition/appreciation to outstanding sports personalities and ...

JOHN DRYABS, YABS DRJOHN. "Kenya's Role in the Implementation of Industrial Development Decate for Africa (I.D.D.A.). A Paper presented at a Regional Workshop on I.D.D.A in Addis Ababa,.". In: An Article in the Underwriter Journal. SITE; Submitted. Abstract

This paper describes the methodology and presents preliminary results of an economic appraisal of a community based health care project in Kenya. Community health workers, trained for 12 weeks and deployed in two locations in Kenya's Western Province, act as first contact providers of basic health care and promoters of selected health, sanitation and nutrition practices. A Cost Benefit Analysis has been undertaken using the Willingness to Pay approach to compare the costs of the project and its benefits. The benefits are in the form of more easily accessible basic health care and are measured as consumer surplus accruing to the community. Gain in consumer surplus is consequent on the fall of average user costs and rise in utilisation of the project established points of first contact with primary health care. The argument for the economic viability of the project is validated by the large Net Present Value and Benefit Cost Ratio obtained for the whole of the project area and for the two locations separately. Although the evaluation technique used faces the problem of valuation of community time, aggregation of health care services at all points of first contact and the partial nature of cost benefit analysis evaluations, the results are strongly in favour of decentralisation of primary health care on similar lines in the rest of the country.

J.S.OLIECH. "Medical Treatment on Bening Prostatic Hyperplasia (BPH) with Combination Drug Therapy.". In: East African Medical JOURNAL. East African Medical Journal; Submitted. Abstract

Obective:To carry out an overview of the medical treatment of the benign prostatic hyperplasia using the combination drugs of alpha adrenergic uro-selective blockers(tamsulocin,alfuzocin) and the 5 alpha reductase iso-enzymes 1&2 inhibitor dutasteride . Data source :Review of researches don and those ongoing especially those sponsored and financed by GlaxoSmithcline in the multicenter international control trials. Data selction: Selected data from international researches on BPH from the following research groups MTOPS,PREDICT,PLESS,VCOOP,ALFIN,DUTASTERIDE 4-DATA 2004/PHASE 111a studies,COmbAT2007,SMART-1, also from GlaxoSmithkline data files.Data Extraction:Selection of research conclusions from various researches tested for clinical use by the international researchers.Data synthesis:From these the advantages of drug compliance  on clinical use on BPH was analysed.                                                                           

Jani PG, Nyaga PN. "Peritonial Drains in Perforated Appendicitis without Generalised Peritonitis:A prospective RandomisedControlled Trail ." East and Central African Journal of Surgery (Online). Submitted;16(2).
JAMES DRMWAURA. "Experiences, Knowledge and Perceptions of Women on Gender Based Violence; A case study of Komu Sub-location, Thika Municipality, Kenya.". In: Kenya Nursing Journal volume 37. National Nurses Association of Kenya; Submitted.
JAMES DRMWAURA. "Gender based violence; A legitimate health concern.". In: Kenya Nursing Journal volume 35. National Nurses Association of Kenya; Submitted.
JAMES DRMWAURA. "Gender based violence; A legitimate health concern.". In: Kenya Nursing Journal volume 35. National Nurses Association of Kenya; Submitted.
JOHN DRYABS. "Insurance Problems of P.T.A. Trade.". In: An Article in the Underwriter Journal. SITE; Submitted. Abstract

This paper describes the methodology and presents preliminary results of an economic appraisal of a community based health care project in Kenya. Community health workers, trained for 12 weeks and deployed in two locations in Kenya's Western Province, act as first contact providers of basic health care and promoters of selected health, sanitation and nutrition practices. A Cost Benefit Analysis has been undertaken using the Willingness to Pay approach to compare the costs of the project and its benefits. The benefits are in the form of more easily accessible basic health care and are measured as consumer surplus accruing to the community. Gain in consumer surplus is consequent on the fall of average user costs and rise in utilisation of the project established points of first contact with primary health care. The argument for the economic viability of the project is validated by the large Net Present Value and Benefit Cost Ratio obtained for the whole of the project area and for the two locations separately. Although the evaluation technique used faces the problem of valuation of community time, aggregation of health care services at all points of first contact and the partial nature of cost benefit analysis evaluations, the results are strongly in favour of decentralisation of primary health care on similar lines in the rest of the country.

J PROFCHINDIAMARK, KAVIN DRWAKOLI. "Koech KJ, Chindia ML, Wakoli KA, Gathece LW. Prevalence of oral lesions in HIV infection and their relationship with CD4 count at a Nairobi centre. African journal of oral health sciences,Vol 5 no2, 4-9.". In: African Journal of Oral Health Sciences,Vol 5 no2, 4-9. Hekima III (1) 27-42; Submitted. Abstract
Savanna ecosystems and origins of modern human behavior Hekima III (1) 27-42: (Journal of the Humanities and Social Sciences, University of Nairobi).
J PROFCHINDIAMARK, KAVIN DRWAKOLI. "Koech KJ, Chindia ML, Wakoli KA, Gathece LW. Prevalence of oral lesions in HIV infection and their relationship with CD4 count at a Nairobi centre. African journal of oral health sciences,Vol 5 no2, 4-9.". In: African Journal of Oral Health Sciences,Vol 5 no2, 4-9. Korean Society of Crop Science and Springer; Submitted. Abstract
OBJECTIVE: To determine the dental caries experience and knowledge on the causes and preventive measures for dental diseases. DESIGN: A community based cross-sectional descriptive study. SETTING: Elwak sub-district hospital, North Eastern Province, Kenya. SUBJECTS: One hundred and forty one adults who presented themselves during a dental check up at a sub-district hospital and gave written consent. MAIN OUTCOME MEASURES: Dental caries status and knowledge on its causes and preventive measures. The importance of outreach programmes in obtaining information as well as helping to alleviate the pain and suffering caused by dental diseases among communities living in remote areas is also revealed. RESULTS: Of the one hundred and forty one individuals, who were included in the study, 63.1% were women and 36.9% were men. Their ages ranged between 18 and over 65 years. 41.1% were in the 18-24-year age bracket. Regarding the oral health knowledge, 43% did not know any causes of dental diseases while 36%, 17% and 12% knew that diet, "dirt" on teeth and bacteria were possible causes, respectively. Fifty percent did not know any preventive measures for dental diseases while the rest indicated abstention from the consumption of sugary foods; and only 0.8% mentioned use of fluoridated toothpaste as a preventive measure for dental caries. 56.7% of the subjects were caries free. The mean DMFT for all ages was 3.4. Of those with caries 72.1% were women. CONCLUSION: There is a low level of oral health awareness and a moderately high level of dental caries experience in this community with women apparently carrying the biggest burden of dental caries.
JOHN DRYABS. "P.T.A - A Promising Market for Kenyan Manufactured Goods.". In: Business Journal, V.III No.12. SITE; Submitted. Abstract

This paper describes the methodology and presents preliminary results of an economic appraisal of a community based health care project in Kenya. Community health workers, trained for 12 weeks and deployed in two locations in Kenya's Western Province, act as first contact providers of basic health care and promoters of selected health, sanitation and nutrition practices. A Cost Benefit Analysis has been undertaken using the Willingness to Pay approach to compare the costs of the project and its benefits. The benefits are in the form of more easily accessible basic health care and are measured as consumer surplus accruing to the community. Gain in consumer surplus is consequent on the fall of average user costs and rise in utilisation of the project established points of first contact with primary health care. The argument for the economic viability of the project is validated by the large Net Present Value and Benefit Cost Ratio obtained for the whole of the project area and for the two locations separately. Although the evaluation technique used faces the problem of valuation of community time, aggregation of health care services at all points of first contact and the partial nature of cost benefit analysis evaluations, the results are strongly in favour of decentralisation of primary health care on similar lines in the rest of the country.

JAMES DRMWAURA, JAMES DRMWAURA, JAMES DRMWAURA. "Relationship between Psychoactive Substance use and High-risk Sexual Practices of Persons Living with HIV/AIDS in Nairobi, Kenya.". In: Kenya Nursing Journal volume 33. National Nurses Association of Kenya; Submitted.
{Capdevielle-Dulac MZ, Balliau T, Ru BL, Kaiser-Arnauld L, Juma G, Maina E, Calatayud P-A. "The use of salivary $\alpha$-amylase as an evolutionary solution to host selection in parasitoids 2.". Submitted. Abstract
n/a
In Press
S. Z, G. C, I. V, G. B, D.M. H, K.M. M, J.R. B. "Adaptive radiation of the endemic Alcolapia cichlids of the East African soda lakes: genetic and morphological perspectives." Journal of Evolutionary Biology. In Press.
JP E, J K, LW I, F H. "Description of pre-adult stages of the coconut bug, Pseudotherapthus wayi ." Journal of Insect Science . In Press.
2022
Ramke J, Evans JR, Habtamu E, Mwangi N, Silva JC, Swenor BK, Congdon N, Faal HB, Foster A, Friedman DS, Gichuhi S, Jonas JB, Khaw PT, Kyari F, Murthy GVS, Wang N, Wong TY, Wormald R, Yusufu M, Taylor H, Resnikoff S, West SK, Burton MJ. "Grand Challenges in global eye health: a global prioritisation process using Delphi method." Lancet Healthy Longev. 2022;3(1):e31-e41. AbstractWebsite

Background: We undertook a Grand Challenges in Global Eye Health prioritisation exercise to identify the key issues that must be addressed to improve eye health in the context of an ageing population, to eliminate persistent inequities in health-care access, and to mitigate widespread resource limitations.

Methods: Drawing on methods used in previous Grand Challenges studies, we used a multi-step recruitment strategy to assemble a diverse panel of individuals from a range of disciplines relevant to global eye health from all regions globally to participate in a three-round, online, Delphi-like, prioritisation process to nominate and rank challenges in global eye health. Through this process, we developed both global and regional priority lists.

Findings: Between Sept 1 and Dec 12, 2019, 470 individuals complete round 1 of the process, of whom 336 completed all three rounds (round 2 between Feb 26 and March 18, 2020, and round 3 between April 2 and April 25, 2020) 156 (46%) of 336 were women, 180 (54%) were men. The proportion of participants who worked in each region ranged from 104 (31%) in sub-Saharan Africa to 21 (6%) in central Europe, eastern Europe, and in central Asia. Of 85 unique challenges identified after round 1, 16 challenges were prioritised at the global level; six focused on detection and treatment of conditions (cataract, refractive error, glaucoma, diabetic retinopathy, services for children and screening for early detection), two focused on addressing shortages in human resource capacity, five on other health service and policy factors (including strengthening policies, integration, health information systems, and budget allocation), and three on improving access to care and promoting equity.

Interpretation: This list of Grand Challenges serves as a starting point for immediate action by funders to guide investment in research and innovation in eye health. It challenges researchers, clinicians, and policy makers to build collaborations to address specific challenges.

QURESHI ZAHIDA, Jamner A, Filippi V, Gwako G, Osoti A, Mehrtash H, Baguiya A, Bello FA, Compaoré R, Gadama L, Kim CR, Msusa AT, Tunçalp Ӧ, Calvert C. "Level and determinants of contraceptive uptake among women attending facilities with abortion-related complications in East and Southern Africa." Int J Gynaecol Obstet. 2022;156 Suppl 1:27-35. Abstract

To investigate the level and determinants of nonreceipt of contraception among women admitted to facilities with abortion-related complications in East and Southern Africa.

Plisnier P-D, Kayanda R, MacIntyre S, Obiero K, Okello W, Vodacek A, Cocquyt C, Abegaz H, Achieng A, Akonkwa B, Albrecht C, Balagizi C, Barasa J, Abel Bashonga R, Bashonga Bishobibiri A, Bootsma H, Borges AV, Chavula G, Dadi T, De Keyzer ELR, Doran PJ, Gabagambi N, Gatare R, Gemmell A, Getahun A, Haambiya LH, Higgins SN, Hyangya BL, Irvine K, Isumbisho M, Jonasse C, Katongo C, Katsev S, Keyombe J, Kimirei I, Kisekelwa T, Kishe M, Otoung A. Koding S, Kolding J, Kraemer BM, Limbu P, Lomodei E, Mahongo SB, Malala J, Mbabazi S, Masilya PM, McCandless M, Medard M, Migeni Ajode Z, Mrosso HD, Mudakikwa ER, Mulimbwa N'sibula, Mushagalusa Déo, Muvundja FA, Nankabirwa A, Nahimana D, Ngatunga BP, Ngochera M, Nicholson S, Nshombo M, Ntakimazi G, Nyamweya C, Ikwaput Nyeko J, Olago D, Olbamo T, O'Reilly CM, Pasche N, Phiri H, Raasakka N, Salyani A, Sibomana C, Silsbe GM, Smith S, Sterner RW, Thiery W, Tuyisenge J, Van der Knaap M, Van Steenberge M, van Zwieten PAM, Verheyen E, Wakjira M, Walakira J, Ndeo Wembo O, Lawrence T. "Need for harmonized long-term multi-lake monitoring of African Great Lakes.". 2022. AbstractWebsite

To ensure the long-term sustainable use of African Great Lakes (AGL), and to better understand the functioning of these ecosystems, authorities, managers and scientists need regularly collected scientific data and information of key environmental indicators over multi-years to make informed decisions. Monitoring is regularly conducted at some sites across AGL; while at others sites, it is rare or conducted irregularly in response to sporadic funding or short-term projects/studies. Managers and scientists working on the AGL thus often lack critical long-term data to evaluate and gauge ongoing changes. Hence, we propose a multi-lake approach to harmonize data collection modalities for better understanding of regional and global environmental impacts on AGL. Climate variability has had strong impacts on all AGL in the recent past. Although these lakes have specific characteristics, their limnological cycles show many similarities. Because different anthropogenic pressures take place at the different AGL, harmonized multi-lake monitoring will provide comparable data to address the main drivers of concern (climate versus regional anthropogenic impact). To realize harmonized long-term multi-lake monitoring, the approach will need: (1) support of a wide community of researchers and managers; (2) political goodwill towards a common goal for such monitoring; and (3) sufficient capacity (e.g., institutional, financial, human and logistic resources) for its implementation. This paper presents an assessment of the state of monitoring the AGL and possible approaches to realize a long-term, multi-lake harmonized monitoring strategy. Key parameters are proposed. The support of national and regional authorities is necessary as each AGL crosses international boundaries.

NW N, J N-M, AN K, M O, C M, T C, MJ O, JM O, S K. " Culture of Kenyan Goat (Capra hircus) Undifferentiated Spermatogonia in Feeder-Free Conditions." Frontiers in Veterinary Science. 2022;9.
J O’o, J M, I O, T A. "Anatomical Variations of the Fifth Lumbar Artery in a sample Kenyan population." Ann Afr surg. 2022;19(2):100-107. AbstractWebsite

bstract
Background: Anatomical variations of lumbar arteries predispose them to iatrogenic injury during endovascular intervention or surgery. Due to limited morphological data on lumbar arteries in our setting, we aimed to determine their variant anatomy among Kenyans.

Methods: We performed the study on 90 cadaveric specimens and 120 computed tomography (CT) scans. Cadavers were dissected to expose the aorta and the lumbar arteries emerging from them. The number, origins, location relative to the vertebral bodies, and relations to aortic bifurcation were determined in cadavers and CT scans. Data were analyzed using SPSS (version 21.0).

Results: On average, 3 (3/90 [3.3%]), 4 (63/90 [70%]) or 5 (24/90 [26.7%]) pairs of lumbar arteries were observed among the cadaveric specimens, whereas 4 (100/120 [83.3%]) or 5 (20/120 [16.7%]) pairs were observed in CTs. Differences in the number of pairs observed in the cadaveric versus CT study were not statistically significant (P = .542). There were no sex differences in the number of lumbar artery pairs observed in CT scans (P = .178). The first 3 lumbar artery pairs had a single-origin, whereas the fourth lumbar artery had a common-stem origin. The first, second, and third lumbar arteries mostly originated at the upper third of their respective vertebral bodies. The fourth lumbar artery predominantly originated at the lower third.

Conclusion: Our study's findings show unique variation in the lumbar arteries' relation to the vertebral bodies and the distances between artery pairs.

Level of evidence: IV (cross-sectional study).

Clinical relevance: Variations in the anatomy of the lumbar arteries should be taken into consideration, especially in surgical or interventional procedures to avoid inadvertent injury of the vessels.

PN R, GO O, O AE, L A, J K. "Assessment of Guideline Concordant Antibiotic Prescribing for Patients with Community Acquired Pneumonia at The Kenyatta National Hospital Medical Wards." Journal of Kenya Association of Physicians. 2022;5(1):34-42. Abstractassessment_of_guideline_concordant_antibiotic_prescribing.pdf

Background: Pneumonia is a major cause of morbidity
and mortality globally. Despite the proven benefits of
guideline concordant antibiotic prescribing, research
has shown that adherence to clinical guideline
recommendations is dismal.
Objectives: The study aims to determine utilization of
Kenyatta National Hospital antibiotic guideline titled
‘The KNH guide to empiric antimicrobial therapy
2018’ in the management of community acquired
pneumonia in the Kenyatta National Hospital medical
wards and the perceived barriers towards the utilization
of this guideline.
Materials and methods: A check list derived from the
Kenyatta National Hospital (KNH) guide to empiric
antimicrobial therapy 2018 was used to assess guideline
concordance based on seven quality indicators:
empiric antibiotic, dose and route of administration,
switch to oral antibiotics, duration of antibiotics (at
least 5 days), collection of microbiological samples
before initiating antibiotics, review of antibiotics at 48
hours and once the culture results are out. Online selfadministered questionnaires were used to determine
attitude and perceived barriers towards utilization
of the KNH guideline among the Internal Medicine
registrars and medical officers.
Analysis: Descriptive statistics were applied in
the representation of each of the seven quality
indicators. These were then compared with the
guideline recommendations and adherence to the
guideline for each parameter was expressed as a
percentage of the total number of patients admitted
with community acquired pneumonia. These were
then graded into the following categories based on the
level of concordance: Good >90%, Intermediate 60-
90%, poor <60%. Questions on the attitude and the
perceived barriers towards KNH guideline utilization
were answered using a 5 point Likert scale. Perceived
barrier statements that were positively formulated
were then recorded so that a lower score meant a
lower level of the perceived barriers and vice versa.
Percentages were then calculated for the total number
of doctors that agreed or strongly agreed that the
barrier was applicable. An open ended question on the
top three barriers to the KNH guideline utilization was
also included in the questionnaire.
Results: For each of the other quality indicators,
adherence to the KNH guideline for patients with
community acquired pneumonia was as follows:
empiric antibiotic choice 48%, collection of samples
for culture prior to antibiotic administration 0%, review
of antibiotics at 48 hours 26.4%, review of antibiotics
with culture results 45.8%, total duration of antibiotics
28.8% and time to switch to oral antibiotics 3.6%. The
top three barriers towards guideline utilization among
the doctors were: unavailability of drugs (52.7%),
inaccessibility of the KNH guideline (45.1%) and lack
of or delay of investigations (34.1%).
Conclusion: This study has demonstrated that the level
of adherence to the seven quality indicators from the
KNH guide is poor with the overall adherence being
35.5%. The recommendation least adhered to was
collection of microbiological samples before initiation
of empiric antibiotics. The most commonly identified
barriers to utilization of the guideline were external
and guideline related barriers.
Key words: Guide to empiric antimicrobial therapy
2018, Guideline Concordance antibiotic prescribing,
Community acquired pneumonia

A. K, Mbugua J. K., A.G. W, Mbui D.N., J. K, I. M, S.O. W. "Bio-Remediation of Lambda Cyhalothrin, Malathion and Chlorpyrifos Using Anaerobic." Digestion Bio-Slurry Microbes. Medicon Agriculture & Environmental Sciences.. 2022;2(5):03-12.
A. K, Mbugua J. K., Mbui D.N., J.G.N. K, I. M, S.O. W. "Bio-Remediation of Lambda Cyhalothrin, Malathion and Chlorpyrifos Using Microbial Fuel Cells. ." International Journal of Scientific Research in Chemistry (IJSRCH). . 2022;7(2):22-32.
Ikanya LW, Maina JG, Gachuiri CK, Owino WO, Jr JCBD. "Chemical Composition and Digestibility of Preferred Forage Species by Lactating Somali Camels in Kenya." Rangeland Ecology & Management. 2022;80:61-67.
Ikanya LW, Maina JG, Gachuiri CK, Owino WO, Jr JCBD. "Chemical Composition and Digestibility of Preferred Forage Species by Lactating Somali Camels in Kenya." Rangeland Ecology & Management. 2022;80:61-67.
Malenje EM, Missohou A, Tebug SF, König EZ, Jung’a JO, Bett RC, Marshall K. "Economic Analysis of Smallholder Dairy Cattle Enterprises In Senegal." research square . 2022.
Malenje EM, Ayao Missohou SFT, König EZ, Jung’a JO, Bett RC, Marshall K. "Economic Analysis of Smallholder Dairy Cattle Enterprises In Senegal.". 2022.
Simon PB, Junga JO, Getinet Mekuriaw Tarekegn, Machuka E, Christian Keambou Tiambo, Kabange D, M KM, Dieudinné RVK, Ochieng JW, Pelle R. "Haplotype analysis of the mitochondrial DNA d-loop region reveals the maternal origin and historical dynamics among the indigenous goat populations in east and west of the Democratic Republic of Congo." Ecology and evolution. 2022;13(2):e8713.
Benard, K.M;. &, M MM, Jeremiah MK. "Individual and Institutional Determinants of Trainees’ Enrolment in Public Technical Vocational Education and Training Institutions in Nakuru County, Kenya." International Journal of Current Science Research and Review. 2022;5(9):3486-3501 .
J.G.N. K, J. NI. "Levels of Essential Elements in selected Persea Americana varieties as Potential Minerals." International Journal of Research and Innovation in Applied Science (IJRIAS). 2022;Accepted on 14th August, 2022.
Johnson L, Onjala J. "Logic of the Belt and Road Initiatives Early Eastern Africa Node: Economic, Demographic and Political Economy Rationales." Journal of Chinese Economic and Foreign Trade Studies,. 2022;accepted January 28 2022.
J.K.M., A.K., M. DN, K JGN, S.O.W, A.G.W. "Microbial Fuel Cell Bio-Remediation of Lambda Cyhalothrin, Malathion and Chlorpyrifos on Loam Soil Inoculated with Bio-Slurry. ." American Journal of Environment and Climate. 2022;1(1):34-41.
N ONURAC, J JAMESG, W MUTHUMBIA, W WANG’ONDUV, A SIGANAD. "Performance of African catfish Clarias gariepinus larvae fed on formulated diets containing Spirulina platensis and Eisenia fetida ." East African Journal of Science, Technology and Innovation. 2022;3(2).
D O, J.N O, A.S O. "Quantification and Characterization of Tannins in Plectranthus barbatus Andrews Water Extracts in Nyamira County, Kenya." Journal of Agriculture and Veterinary Sciences. . 2022;Articles in Press.
Ngwili N, Thomas L, Wahome RG, Githigia S, Johnson N, Roesel K. "Stakeholders' Knowledge, Attitude, and Perceptions on the Control of Taenia solium in Kamuli and Hoima Districts, Uganda." Frontiers in Veterinary Science. 2022:363.
Ngwili N, Thomas L, Githigia S, Johnson N, Raphael Wahome KR. "Stakeholders' Knowledge, Attitude, and Perceptions on the Control of Taenia solium in Kamuli and Hoima Districts, Uganda." Frontiers in Veterinary Science. 2022:363.
K G, T M, J N, MO O. "Studies on the ethnopharmacology, antimicrobial activity, and toxicity of Catha edulis (Vahl.) Endl., in Sprague Dawley rats.". 2022;([version 1; peer review: awaiting peer review]. F1000 Research 2022, 11:286):https://doi.org/10.12688/f1000research.109243.1.
Osiro OO, Kariuki DK, Joyce K G. "Synthesis and Characterization of Ionomer-type Cements from Alkalin-Activated Kaolinite." Journal of Non-Crystalline Solids-X. 2022;13(100079):2-10.
J O’o, BN B, V M, I C. "The Unusual High Origin Radial Artery in a Black Kenyan Population; a Cadaveric Study." Ethiop J Health SCI. 2022;32(2):445-452. Abstract223352-article_text-545874-1-10-20220328.pdfWebsite

Abstract
BACKGROUND: The anatomy of the radial artery draws great interests among anatomists for its frequent involvement in variations. Equally, these variations have gained significant attention from clinicians because of the preference to use the radial artery for catheterization. The commonest of radial artery variations involve its site of origin. In published literature, data on this variations exist, but the prevalence of such variations in a Kenyan population has hitherto been unknown.
METHODS: Sixty-two upper limbs from 50 formalin-fixed cadavers were studied during dissection in the Department of Human Anatomy, University of Nairobi.
RESULTS: Fifty-four (87.1%) radial arteries arose within the cubital fossa, while eight (12.9%) had a high origin. Out of the eight high arteries, two (3.2%) branched off from the axillary artery, another two (3.2%) were branches of the proximal third of the brachial artery and four (6.5%) arose from the middle third of the brachial artery. The high origin radial arteries were more common on the right upper limbs (5 out of the 8 cases). Both axillary and brachial origins were seen bilaterally.
CONCLUSION: The present study details important variations in the anatomy of the radial artery in a Kenyan population. With the radial artery being utilized during clinical, surgical and radiological interventions so frequently, an increased understanding and anticipation of such topographic variances is paramount.

Elkanah O, Jonathan Y, Shanthi M, Campbell Z€A, Thumbi SM, Njagi LW, Nyaga PN, Palmer GH. "Vaccination of household chickens results in a shift in young children’s diet and improves child growth in rural Kenya." PNAS. Economic Sciences Agricultural Sciences. 2022;Volume 119(No. 24).
A. K, Mbugua J. K., Mbui D.N., J. K, I. M, S.O. W. "Voltage Recovery from Pesticides Doped Tomatoes, Cabbages and Loam Soil Inoculated with Rumen Waste: Microbial Fuel Cells. ." International Journal of Scientific Research in Science, Engineering and Technology (IJSRSET).. 2022;9(2):172-180.
Odhiambo T, J K. "The ‘Perplexing African in China’: A Reading of Black Ghosts by Ken Kamoche." Journal of Language, Technology and Entrepreneurship in Africa . 2022;13(1):63-74.
Deng Y, Liu L, Li MY, Jiang M, Peng B, Yang Y. "A data-driven wheel wear prediction model for rail train based on LM-OMP-NARXNN." Journal of Computing and Information Science in Engineering. 2022:1-11. Abstract
n/a
Zhang J, Peng B, Kim S, Monifi F, Jiang X, Li Y, Yu P, Liu L, Liu Y-xi, Alu A, others. "Optomechanical dissipative solitons (vol 600, pg 75, 2021)." NATURE. 2022. Abstract
n/a
Zhang J, Peng B, Kim S, Monifi F, Jiang X, Li Y, Yu P, Liu L, Liu Y-xi, Alù A, others. "Publisher Correction: Optomechanical dissipative solitons." Nature. 2022. Abstract
n/a
2021
Umuhoza T, Bulimo WD, Julius Oyugi, Musabyimana JP, Kinengyere AA, Mancuso JD. "Prevalence of human respiratory syncytial virus, parainfluenza and adenoviruses in East Africa Community partner states of Kenya, Tanzania, and Uganda: A systematic review and meta-analysis (2007–2020)." PLOS ONE. 2021;16(4):e0249992-. Abstractjournal.pone_.0249992.pdfjournal.pone_.0249992.pdfWebsite

Background Viruses are responsible for a large proportion of acute respiratory tract infections (ARTIs). Human influenza, parainfluenza, respiratory-syncytial-virus, and adenoviruses are among the leading cause of ARTIs. Epidemiological evidence of those respiratory viruses is limited in the East Africa Community (EAC) region. This review sought to identify the prevalence of respiratory syncytial virus, parainfluenza, and adenoviruses among cases of ARTI in the EAC from 2007 to 2020. Methods A literature search was conducted in Medline, Global Index Medicus, and the grey literature from public health institutions and programs in the EAC. Two independent reviewers performed data extraction. We used a random effects model to pool the prevalence estimate across studies. We assessed heterogeneity with the I2 statistic, and Cochran’s Q test, and further we did subgroup analysis. This review was registered with PROSPERO under registration number CRD42018110186. Results A total of 12 studies met the eligibility criteria for the studies documented from 2007 to 2020. The overall pooled prevalence of adenoviruses was 13% (95% confidence interval [CI]: 6–21, N = 28829), respiratory syncytial virus 11% (95% CI: 7–15, N = 22627), and parainfluenza was 9% (95% CI: 7–11, N = 28363). Pooled prevalence of reported ARTIs, all ages, and locality varied in the included studies. Studies among participants with severe acute respiratory disease had a higher pooled prevalence of all the three viruses. Considerable heterogeneity was noted overall and in subgroup analysis. Conclusion Our findings indicate that human adenoviruses, respiratory syncytial virus and parainfluenza virus are prevalent in Kenya, Tanzania, and Uganda. These three respiratory viruses contribute substantially to ARTIs in the EAC, particularly among those with severe disease and those aged five and above.

Ogana W, Juma VO, Bulimo WD. "A SIRD model applied to COVID-19 dynamics and intervention strategies during the first wave in Kenya." medRxiv. 2021:2021.03.17.21253626. AbstractWebsite

The first case of COVID-19 was reported in Kenya in March 2020 and soon after non-pharmaceutical interventions (NPIs) were established to control the spread of the disease. The NPIs consisted, and continue to consist, of mitigation measures followed by a period of relaxation of some of the measures. In this paper, we use a deterministic mathematical model to analyze the dynamics of the disease, during the first wave, and relate it to the intervention measures. In the process, we develop a new method for estimating the disease parameters. Our solutions yield a basic reproduction number, R0 = 2.76, which is consistent with other solutions. The results further show that the initial mitigation reduced disease transmission by 40% while the subsequent relaxation increased transmission by 25%. We also propose a mathematical model on how interventions of known magnitudes collectively affect disease transmission rates. The modelled positivity rate curve compares well with observations. If interventions of unknown magnitudes have occurred, and data is available on the positivity rate, we use the method of planar envelopes around a curve to deduce the modelled positivity rate and the magnitudes of the interventions. Our solutions deduce mitigation and relaxation effects of 42.5% and 26%, respectively; these percentages are close to values obtained by the solution of the SIRD system. Our methods so far apply to a single wave; there is a need to investigate the possibility of extending them to handle multiple waves.Competing Interest StatementThe authors have declared no competing interest.Clinical TrialNot a clinical trialFunding StatementNo funding supportAuthor DeclarationsI confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.YesThe details of the IRB/oversight body that provided approval or exemption for the research described are given below:KNH-UoN Ethics and Research Committee https://erc.uonbi.ac.keAll necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived.YesI understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance).YesI have followed all appropriate research reporting guidelines and uploaded the relevant EQUATOR Network research reporting checklist(s) and other pertinent material as supplementary files, if applicable.YesData sources: All the data used is in the public domain [1, 44, 56, 57]

Lubembe DM, Odongo DO, Joubert F, Sibeko-Matjila KP. "Limited diversity in the CD8+ antigen-coding loci in Theileria parva parasites from cattle from southern and eastern Africa." Vet Parasitol. 2021;291:109371. Abstract

Theileria parva infections in cattle causes huge economic losses in the affected African countries, directly impacting the livelihood of the poor small-holder farmers. The current immunization protocol using live sporozoites in eastern Africa, is among the control measures designed to limit T. parva infections in cattle. However, the ability of the immune protection induced by this immunization to protect against field parasites has been compromised by the diversity of the parasite involving the schizont antigen genes. Previous studies have reported on the antigenic diversity of T. parva parasites from southern and eastern Africa, however, similar reports on T. parva parasites particularly from cattle from southern Africa remains scanty, due to the self-limiting nature of Corridor disease. Thus, we evaluated the diversity of CD8+ T-cell regions of ten schizont antigen genes in T. parva parasites associated with Corridor disease and East Coast fever (ECF) from southern and eastern Africa respectively. Regions of schizont antigen (TpAg) genes containing the CD8+ T-cell epitopes (CTL determinants) were amplified from genomic DNA extracted from blood of T. parva positive samples, cloned and sequenced. The results revealed limited diversity between the two parasite groups from cattle from southern and eastern Africa, defying the widely accepted notion that antigen-encoding loci in cattle-derived parasites are conserved, while in buffalo-derived parasites, they are extensively variable. This suggests that only a sub-population of parasites is successfully transmitted from buffalo to cattle, resulting in the limited antigenic diversity in Corridor disease parasites. Tp4, Tp5, Tp7 and Tp8 showed limited to absence of diversity in both parasite groups, suggesting the need to further investigate their immunogenic properties for consideration as candidates for a subunit vaccine. Distinct and common variants of Tp2 were detected among the ECF parasites from eastern Africa indicating evidence of parasite mixing following immunization. This study provides additional information on the comparative diversity of TpAg genes in buffalo- and cattle-derived T. parva parasites from cattle from southern and eastern Africa.

Gwako GN, Obimbo MM, Gichangi PB, John Kinuthia, James N Kiarie, Gachuno OW, Were F. "Association between obstetric and medical risk factors and stillbirths in a low-income urban setting." Int J Gynaecol Obstet. 2021;154(2):331-336. Abstract

To evaluate the association between obstetric and medical risk factors and stillbirths in a Kenyan set-up.

Baguiya A, Bonet M, Cecatti JG, Brizuela V, Curteanu A, Minkauskiene M, Jayaratne K, Ribeiro-do-Valle CC, Budianu M-A, Souza JP, Kouanda S. "Perinatal outcomes among births to women with infection during pregnancy." Arch Dis Child. 2021;106(10):946-953. Abstract

This study is part of the Global Maternal Sepsis Study (GLOSS). It aimed to estimate neonatal near-miss (NNM) and perinatal death frequency and maternal risk factors among births to women with infection during pregnancy in low-income and middle-income countries (LMIC).

Baguiya A, Bonet M, Cecatti JG, Brizuela V, Curteanu A, Minkauskiene M, Jayaratne K, Ribeiro-do-Valle CC, Budianu M-A, Souza JP, Kouanda S. "Perinatal outcomes among births to women with infection during pregnancy." Arch Dis Child. 2021;106(10):946-953. Abstract

This study is part of the Global Maternal Sepsis Study (GLOSS). It aimed to estimate neonatal near-miss (NNM) and perinatal death frequency and maternal risk factors among births to women with infection during pregnancy in low-income and middle-income countries (LMIC).

Gwako GN, Were F, Obimbo MM, John Kinuthia, James N Kiarie, Gachuno OW, Gichangi PB. "Association between utilization and quality of antenatal care with stillbirths in four tertiary hospitals in a low-income urban setting." Acta Obstet Gynecol Scand. 2021;100(4):676-683. Abstract

About 2.6 million stillbirths per year occur globally with 98% occurring in low- and middle-income countries including Kenya, where an estimated 35 000 stillbirths occur annually. Most studies have focused on the direct causes of stillbirth. The aim of this study was to determine the association between antenatal care utilization and quality with stillbirth in a Kenyan set up. This information is key when planning strategies to reduce the stillbirth burden.

Burton MJ, Ramke J, Marques AP, Bourne RRA, Congdon N, Jones I, Ah Tong BAM, Arunga S, Bachani D, Bascaran C, Bastawrous A, Blanchet K, Braithwaite T, Buchan JC, Cairns J, Cama A, Chagunda M, Chuluunkhuu C, Cooper A, Crofts-Lawrence J, Dean WH, Denniston AK, Ehrlich JR, Emerson PM, Evans JR, Frick KD, Friedman DS, Furtado JM, Gichangi MM, Gichuhi S, Gilbert SS, Gurung R, Habtamu E, Holland P, Jonas JB, Keane PA, Keay L, Khanna RC, Khaw PT, Kuper H, Kyari F, Lansingh VC, Mactaggart I, Mafwiri MM, Mathenge W, McCormick I, Morjaria P, Mowatt L, Muirhead D, Murthy GVS, Mwangi N, Patel DB, Peto T, Qureshi BM, Salomão SR, Sarah V, Shilio BR, Solomon AW, Swenor BK, Taylor HR, Wang N, Webson A, West SK, Wong TY, Wormald R, Yasmin S, Yusufu M, Silva JC, Resnikoff S, Ravilla T, Gilbert CE, Foster A, Faal HB. "The Lancet Global Health Commission on Global Eye Health: vision beyond 2020." Lancet Glob Health. 2021;9(4):e489-e551.Website
Vogel JP, Comrie-Thomson L, Pingray V, Gadama L, Galadanci H, Goudar S, Rose Laisser, Lavender T, Lissauer D, Misra S, Pujar Y, Qureshi ZP, Amole T, Berrueta M, Dankishiya F, Gwako G, Homer CSE, Jobanputra J, Meja S, Nigri C, Mohaptra V, Osoti A, Roberti J, Solomon D, Suleiman M, Robbers G, Sutherland S, Vernekar S, Althabe F, Bonet M, Oladapo OT. "Usability, acceptability, and feasibility of the World Health Organization Labour Care Guide: A mixed-methods, multicountry evaluation." Birth. 2021;48(1):66-75. Abstract

The World Health Organization's (WHO) Labour Care Guide (LCG) is a "next-generation" partograph based on WHO's latest intrapartum care recommendations. It aims to optimize clinical care provided to women and their experience of care. We evaluated the LCG's usability, feasibility, and acceptability among maternity care practitioners in clinical settings.

Okumu MO, Mbaria JM, Gikunju JK, Mbuthia PG, Madadi VO, Ochola FO, Jepkorir MS. "Artemia salina as an animal model for the preliminary evaluation of snake venom-induced toxicity. .". In: 7th All Africa Congress of Pharmacology . Virtual; 2021.
MM B, M B, J F, EA L, A A, K A, GA B, WD B, E B, C C, H D, P D'A, L DC, N F, A M. "Diagnostic performance of a colorimetric RT -LAMP for the identification of SARS-CoV-2: A multicenter prospective clinical evaluation in sub-Saharan Africa." EClinicalMedicine. 2021. Abstract
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Nicholas B, Derrick S, Dorcas C, Patrick M, Joshua O, Thomas LF. "). Food Safety & Animal Welfare in the Pork Value Chain of Nairobi.". 2021:DOI: 10.17638/datacat.liverpool.ac.uk/1441.
Josephine Wangechi Kirui, Muthama NJ, Gachuiri CK, Ngaina JN. "Adaptation and mitigation strategies to climate change by smallholder dairy farmers: A case of Nandi county in Kenya." Journal of Sustainability, Environment and Peace. 2021;4(1):39-47.
Jepkoech C, Omosa LK, Nchiozem-Ngnitedem V-A, Kenanda EO, Guefack M-GF, Mbaveng AT, Kuete V, Heydenreich M. "Antibacterial secondary metabolites from Vernonia auriculifera Hiern (Asteraceae) against MDR phenotypes." Natural Products Research. 2021:https://doi.org/10.1080/14786419.2021.1953024.jepkoech_et_al_2021_natural_products_research.pdf
Armah FA, Henneh IT, Amponsah IK, Biney RP, F M, J A, W A, Ahmed MA, Adokoh CK, Adukpo G, O AD, Gathumbi PK. "Antidepressant and Anxiolytic Effects and Subchronic Toxicity of the Aerial Parts of Psychotria ankasensis J.B.Hall (Rubiaceae) in Murine Models." Hindawi Veterinary Medicine International. 2021;Volume 2021, Article ID 5543320, 18 pages.armah_et_al_2021.pdf
Juma M, Sankaradoss A, Ndomb R, Mwaura P, Damodar T, Nazir J, Pandit A, Khurana R, Masika M, Chirchir R, Gachie J, Krishna S, Sowdhamin R, Anzala O, Iyer MS. "Antimicrobial resistance profiling and phylogenetic analysis of Neisseria gonorrhoeae clinical isolates from Kenya in resource limited setting." Frontiers in Microbiology. 2021. AbstractWebsite

Background: Africa has one of the highest incidences of gonorrhea. Neisseria gonorrhoeae is gaining resistance to most of the available antibiotics, compromising treatment across the world. Whole-genome sequencing (WGS) is an efficient way of predicting AMR determinants and their spread in the population. Recent advances in next-generation sequencing technologies like Oxford Nanopore Technology (ONT) have helped in the generation of longer reads of DNA in a shorter duration with lower cost. Increasing accuracy of base-calling algorithms, high throughput, error-correction strategies, and ease of using the mobile sequencer MinION in remote areas lead to its adoption for routine microbial genome sequencing. To investigate whether MinION-only sequencing is sufficient for WGS and downstream analysis in resource-limited settings, we sequenced the genomes of 14 suspected N. gonorrhoeae isolates from Nairobi, Kenya.

Methods: Using WGS, the isolates were confirmed to be cases of N. gonorrhoeae (n = 9), and there were three co-occurrences of N. gonorrhoeae with Moraxella osloensis and N. meningitidis (n = 2). N. meningitidis has been implicated in sexually transmitted infections in recent years. The near-complete N. gonorrhoeae genomes (n = 10) were analyzed further for mutations/factors causing AMR using an in-house database of mutations curated from the literature.

Results: We observe that ciprofloxacin resistance is associated with multiple mutations in both gyrA and parC. Mutations conferring tetracycline (rpsJ) and sulfonamide (folP) resistance and plasmids encoding beta-lactamase were seen in all the strains, and tet(M)-containing plasmids were identified in nine strains. Phylogenetic analysis clustered the 10 isolates into clades containing previously sequenced genomes from Kenya and countries across the world. Based on homology modeling of AMR targets, we see that the mutations in GyrA and ParC disrupt the hydrogen bonding with quinolone drugs and mutations in FolP may affect interaction with the antibiotic.

Conclusion: Here, we demonstrate the utility of mobile DNA sequencing technology in producing a consensus genome for sequence typing and detection of genetic determinants of AMR. The workflow followed in the study, including AMR mutation dataset creation and the genome identification, assembly, and analysis, can be used for any clinical isolate. Further studies are required to determine the utility of real-time sequencing in outbreak investigations, diagnosis, and management of infections, especially in resource-limited settings.

Okumu MO, Mbaria JM, Gikunju JK, Mbuthia PG, Madadi VO, Ochola FO, Jepkorir MS. "Artemia salina as an animal model for the preliminary evaluation of snake venom-induced toxicity." Toxicon. 2021;(X12 (2021) 100082.).
Okumu MO, Mbaria JM, Gikunju JK, Mbuthia PG, Madadi VO, Ochola FO, Jepkorir MS. "Artemia salina as an animal model for the preliminary evaluation of snake venominduced toxicity." Toxicon. DOI: https://doi.org/10.1016/j.toxcx.2021.100082. 2021.
AM J, CAZ J, AEB H, JA O’o. "Bilateral Ligation of the Anterior Branch of the Hypogastric Artery in Massive Obstetric Hemorrhage Secondary to Septic Abortion (Case Report)." J Gynecol Obstet. 2021;3(9):92-99. AbstractWebsite

Abstract
Hemorrhage is the main cause of Maternal Mortality (MM) (27%) followed by hypertensive disorders and sepsis (12%). Septic abortion is considered an intermediate risk factor for the development of Massive Obstetric Hemorrhage (MOH). The algorithm for the management of postpartum hemorrhage due to uterine atony that includes systematic pelvic devascularization has been described, but this management is really planned for resolution of the pregnancy after the 20th week of gestation, since an HMO due to abortion is un usual. We present the case of a 21-year-old patient who self-medicates a prostaglandin analog at 2 months of pregnancy, achieving only a threat of abortion, goes to the emergency room 3 months later with a diagnosis of septic shock, USG and MRI are performed with altered results, only of hepatomegaly, delayed abortion of 8 weeks of evolution and gestational trophoblastic disease. Emergency MVA was performed due to profuse bleeding, placement of a Bakri balloon and clamping of the uterine arteries without results, for which an emergency exploratory laparotomy (LAPE) was performed with ligation of the anterior trunk of the internal iliac artery, being a successful procedure, without the need for Obstetric Hysterectomy (HO). The patient is managed in intensive care and in the end the diagnosis of TSG is ruled out. Bilateral Hypogastric Artery Ligation (BHAL) in the case of Massive Obstetric Hemorrhage (MOH) secondary to delivery or cesarean section is commonly used, however it is not a technique to report when bleeding is secondary to abortion. In these cases, it is also a viable, successful, fertility-preserving surgical procedure, and an alternative to Obstetric Hysterectomy (OH) when other less invasive methods such as uterine artery clamping or Bakri balloon have failed.

Imwene K.O., Mbui D.N., Kinyua, Gladys Wanjiru, J.K M, Ahenda S, Onyatta JO. "Biotransformation of Biodegraded Organic Waste from a Batch Mode Microbial Fuel Cell to Organic Fertilizer." J. Bioremediat Biodegrad. . 2021;12(8):1-5.
Heylen D, Day M, Schunack B, Fourie J, Labuschange M, Johnson S, Samuel Maina Githigia, Akande FA, Nzalawale JS. "A community approach of pathogens and their arthropod vectors (ticks and fleas) in dogs of African Sub-Sahara." Parasites & Vectors. 2021;2021(14:576):1-20.
O OGUMOE, N. KC, J. KIMENJU, MW O. "Comparison of the efficiency of solar-powered prototype vapour compression cooler with evaporative charcoal cooler in maintaining quality of French beans ." East African Journal of Science, Technology and Innovation,. 2021;2(Special issue).
Kinyua A. P., Mbugua J. K., Imwene K.O., Mbui D.N., J.G.N. K, S.O. W, I. M. "Current and voltage data logging from microbial fuel cells using Arduino based sensors." International Robotics & Automation Journal. 2021;7(3):90-93.abstract.pdf
Malembaka REB, Onwonga R, Jefwa J, Ayuke F, Nabahungu L. "Diversity and distribution of arbuscular mycorrhizal fungi in maize (Zea mays) cropping fields in South Kivu, Democratic Republic of Congo." African Journal of Agricultural Research. 2021;17(4):604-617.
FW N, Ouyang K AA, J O'o, GW A, D Z. "Does Keloid Histology Influence Recurrence?" Am J Dermatol. doi. 2021;10(PMID: 33464754.). AbstractWebsite

Abstract
Keloids are fibroproliferative disorders characterized by high recurrence rates, with few factors known to influence the same. We conducted a study to determine whether keloid histology influences recurrence. This was a prospective longitudinal study to determine whether histopathological parameters of keloid influence recurrence. Patients with keloids managed by surgical excision were followed up at Kenyatta National Hospital between August 2018 and July 2020. The excised keloids were processed for histology using hematoxylin,/eosin, Masson, and trichrome stains. The slides were analyzed for inflammatory cells, fibroblasts, and capillary density using the hot spot technique and correlated to keloid recurrence. Postoperative follow-up was for a minimum of 1 year. A total of 90 patients with 104 keloids were recruited in the study. Overall keloid recurrence rate was 28.6%. There was a correlation between the absolute count of more than 50 per High power field of lymphocytes, fibroblasts, and macrophages with recurrence of the disease. The sensitivity and specificity for the above parameters were lymphocytes 48% and 81%, macrophages 57% and 83%, mast cells 32% and 33%, and fibroblasts 41% and 91%, respectively. There was no correlation between mast cells and vascularity status with recurrence. Routine histology should, therefore, be performed to determine these parameters. Close monitoring and second-line therapy should be considered for patients with elevated macrophages and/or lymphocytes so as to reduce the risk of recurrence.

MO F, ME T, JI V, CA F, M R, AM K, R V, OB A‐B, R A, B G, SZ M, A A, H D, A V, RJ S, for the Group ECCA. "An ecological study on the association between universal health service coverage index, health expenditures, and early childhood caries." BMC Oral Health. 2021;2021; 21:126.(2021; 21:126.):2021; 21:126.
F M, F. M, J. N. "Effect of Employee reward, on employee performance at the Kenya Police service." European Jounrnal of Business and Management. 2021;13(2).
Mwinami T, Junga JO, Oduma JA, Chesire D, Musina J, Kioko E, Ayiemba W, Harper DM. "EFFECT OF FOREST FRAGMENTATION ON AVIAN SPECIES COMPOSITION, DIVERSITY AND DISTRIBUTION WITHIN AN UPLAND TROPICAL FOREST ECOSYSTEM:.". 2021.
Judy Kimaru1*, Henry Mutembei2 JKM2. "Effectiveness of Drought Risk Reduction Policies: Case Study of Hay Production in Kajiado County, Kenya." American journal of Climate Change. 2021;(10):512-532.
Jerop B, Segera DR. "An Efficient PCA-GA-HKSVM-Based Disease Diagnostic Assistant." Hindawi Biomed Research International. 2021;2021(2021):1-10.
J. MMMNFFM. "Employee reward, work environment and employee performance at the Kenya Police service,." DBA Africa Management Review . 2021;11(1).
JW G, J O’o, P G. "Endometriosis Diagnosis correlation of Laparoscopic visualization and histopathology confirmation in low Resource setting." Open J Obs Gyne. 2021;11(7):845-852. Abstractojog_2021071515313873.pdfWebsite

Abstract

Background: Endometriosis is enigmatic clinical entity which is described as the location of the endometrial tissue external of the uterine cavity. Endometriosis constitutes a serious health issue due to its high affliction of 10% of reproductive women. With limited resources in Africa, it is essential to assess whether diagnosis of endometriosis by laparoscopic visualization can be used as a substitute for histology. Objective: To correlate the diagnosis of endometriosis by laparoscopic visualization and the histological confirmation of the biopsy taken. Methods: A prospective cross sectional study with a sample size of 443 was undertaken in the diagnosis of endometriosis among Africans in Nairobi, Kenya from March 2019 to March 2021. Women undergoing laparoscopy were screened for endometriosis by visualization and a biopsy was taken for histopathology. Diagnosis of endometriosis by visualization was correlated with histological confirmed endometriosis. Results: Women with a diagnosis of endometriosis through laparoscopic visualization were found to be 77 (17.4%) and 30 (6.8%) had positive histology for endometriosis. Laparoscopic visualization diagnosis had a low positive predictive value of 39%. Conclusion: Laparoscopic visualization diagnosis had a low positive predictive value of 39% and this did not correlate with histopathologic diagnosis. It is essential to perform biopsy with histopathology for the confirmation of endometriosis.

3. Onwonga RN, Chemining’wa GN, Jumbo MB. "Enhancing yellow maize production for sustainable food and nutrition security in African ." Journa Kenya. East l of Science, Technology and Innovation. 2021;2(1):00.
A A Fabuyide, Cornish LA, Apata AO, Rading GO, Muobeni TN, Witcomb MJ, Jain PK, Borode JO. "Experimental Liquidus Surface Projection and Isothermal Section at 1000C of the V-Ni-C System, J of Phase Equilibria and Diffusion.". 2021.
Peter M. F. Mbithi, Judith S. Mbau, Nzioka J. Muthama, Hellen Inyega JKM, Kala JM. "Higher education and skills development in Africa: An analytical paper on the role of higher learning Institutions on sustainable development." Journal of Sustainability, Environment & Peace. 2021;4(2):58-73.
Peter K, John VL, George G, Luke H, Shawn MK, Spencer G. "Impact of calf housing improvement and farmer training on finances, management and animal welfare perceptions of Kenyan smallholder dairy farmers." Journal of Development and Agricultural Economics. 2021;13(2):119-129.
Wangai M M, Inyega JO, M M, JM. K. "Influence of ISO 9001 standards on quality of academic programmes in universities in Kenya: a case of bachelor of education programme of the University of Nairobi." Journal of Pedagogy, Andragogy and Heutagogy in Academic Practice. 2(2):34-48.. 2021;2(2):34-48.
Musyoki J, J.A O. "Influence of Principals Inspirational Influence on Students Performance at Kenya Certificate of Secondary Education in Public Secondary Schools, Kenya." IOSR Journal of Humanities and Social Science 2. 2021;26(2279-0837):10.9790/0837-2605094760.
Wangai M M, Inyega J, M M, J. K. "Influence of Total Quality Management and Knowledge Management on Quality of University Academic Programmes: A Literature Review." Journal of Pedagogy, Andragogy and Heutagogy in Academic Practice. . 2021;2(1):1-14.
I C, P S, B N, M M, JA O’o. "Laparoscopic surgery during the COVID-19 pandemic: detection of SARS-COV-2 in abdominal tissues, fluids, and surgical smoke." Langenbecks Arch Surg. 2021;406(4):1007-1014. AbstractWebsite

Abstract
Background: There are still concerns over the safety of laparoscopic surgery in coronavirus disease 2019 (COVID-19) patients due to the potential risk of viral transmission through surgical smoke/laparoscopic pneumoperitoneum.

Methods: We performed a systematic review of currently available literature to determine the presence of severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) in abdominal tissues or fluids and in surgical smoke.

Results: A total of 19 studies (15 case reports and 4 case series) comprising 29 COVID-19 patients were included. The viral RNA was positively identified in 11 patients (37.9%). The samples that tested positive include the peritoneal fluid, bile, ascitic fluid, peritoneal dialysate, duodenal wall, and appendix. Similar samples, together with the omentum and abdominal subcutaneous fat, tested negative in the other patients. Only one study investigated SARS-COV-2 RNA in surgical smoke generated during laparoscopy, reporting negative findings.

Conclusions: There are conflicting results regarding the presence of SARS-COV-2 in abdominal tissues and fluids. No currently available evidence supports the hypothesis that SARS-COV-2 can be aerosolized and transmitted through surgical smoke. Larger studies are urgently needed to corroborate these findings.

Japheth NR, Rukwaro PR, Wachira-Towey IN. "Management of Steel Reinforcement Works Procedures Impact on the Health of Workers in Building Construction Sites Case study of Nairobi County, Kenya." Journal of Entrepreneurship & Project management. 2021;Volume 5(1).
FW N, K O, A A, J O, GW A. "Multiple Cytokines Elevated in Patients with Keloids: Is It an Indication of Auto-Inflammatory Disease?" J. Inflam Res. 2021;14(7):2465-2470. AbstractWebsite

Abstract
Background: Inflammation seems to play a major role in the pathophysiology of keloids. However, the role of cytokines in keloid pathophysiology has not been fully evaluated with only a few cytokines studied. We undertook this study to compare various cytokines in patients with keloids and a control group of patients without keloids nor family history of keloids so as to determine which cytokines are elevated and could thus be critical in keloid formation.

Methods: This was a cross-sectional study of patients with keloids and a control group of those without. Patients in both groups were matched for age, sex and body mass index. Their plasma was analyzed for both inflammatory and anti-inflammatory cytokines using the Bio-flex ElisaTM method. Comparisons of cytokines means in both groups were done using Student's t-test.

Results: A total of 84 participants with 42 participants in each group were followed during the study. Male to female ratio was 1:2. Age ranges were similar with a mean of 29.6 years. A total of 28 cytokines were assayed. Statistically significant differences were noted in 15 of the 28 cytokines assayed with 11 being elevated more in keloid patients with only four in the non-keloid forming group. Among elevated cytokines in keloid patients were granulocyte colony-stimulating factors, granulocyte-monocyte-colony-stimulating factors, interleukins 4, 6 and 13.

Conclusion: Patients with keloids have significantly higher cytokines compared with non-keloid forming patients. This finding suggests that keloid formation could be influenced by multiple inflammatory cytokines, an indication that the patient's immune system could play a role in keloid formation akin to auto-inflammatory disease.

JW G, J O’o, P G. "Pattern and Clinical Presentation of Endometriosis Among the Indigenous Africans." J Gynecol Obstet . 2021;9(9):92-99. AbstractWebsite

Abstract
Background: Endometriosis is enigmatic clinical entity which is described as the existence of the endometrial tissue external of the uterine cavity. Endometriosis constitutes a serious health issue due to its high affliction of 10% in reproductive age women and its clinical manifestation of infertility and chronic pelvic pain. Despite of years of research, the causative factor and understanding of ambidextrous endometriosis pathology remains elusive, perplex and disconnected. Worldwide, there is clear documentation of prevalence of endometriosis in the development countries, however, the prevalence of endometriosis in most of black Africa is unknown. The current perspective is that indigenous African are rarely affected by endometriosis. Objective: To determine the prevalence, pattern and clinical presentation of endometriosis in indigenous African women with the primary outcome measure being the prevalence of laparoscopic visually diagnosed, histologically confirmed endometriosis and clinical presentation. Methodology: This was a prospective analytical cross-selection study in 2 hospitals in Nairobi city, Kenya. The sample size was 443 women and the duration of the study was from March 2018 to March 2021. The inclusion criteria was women aged at least 18 years up to 49 years undergoing laparoscopic surgery and willing to take part in the study. The patient’s history, clinical and laparoscopic findings and histological diagnosis were recorded and analysed using Social SPSS version 22.0. Results: The mean age of the 443 patients recruited was 33 years. The prevalence of histological confirmed endometriosis in indigenous Africans was 6.8%. Laparoscopic visualization diagnosis had a positive predictive value of 39%. Dysmenorrhoea, chronic pelvic pain scale 8-10 and dyspareunia were significant symptoms of endometriosis P<0.001. Nulliparous patients significantly had a risk of having endometriosis p<0.001. The patients with menarche at 13 years and below had a significant risk of having endometriosis p=0.001. Physical findings on clinical examination of adnexal tenderness and findings of nodules in the pouch of Douglas were significant in relation to endometriosis p<0.001. The most common site of the histological endometriosis implants were on the Pouch of Douglas (30%) and the most common form of endometriosis was superficial (43%). Conclusion: The prevalence of endometriosis in Indigenous Africa is 6.8%. Laparoscopic visualization diagnosis had low a positive predictive value of 39%. Nulliparity, menarche at the age of 13 and below, dysmenorrhoea, chronic pelvic pain scale 8-10 and dyspareunia were significantly associated with endometriosis. The most common site for endometriosis is the of Pouch of Douglas whilst the most common form of endometriosis was superficial.

Karuma AN, JW N, PT G. "Pedology, A disappearing skill in Eastern Africa? A Review." Tropical and Subtropical Agroecosystems. 2021;24(2):65.
Simon Patrick Baenyi, Junga JO, et.al. "Phenotypic traits,reproductive and milk performance of indigenous goats of south Kivu, Democratic Republic of Congo." Journal of Dairy, Veterinary and Animal Research. 2021;(Submitted).
M.Cecilia O, Justine NM, Johanna W, Mats S, Piikki K. "Precision Agriculture for Resource Use Efficiency in Smallholder Farming Systems in Sub-Saharan Africa: A Systematic Review." Sustainability Journal. 2021;13:1158.
M.Justine N, Cecilia OM, Johanna W, Mats S. "Precision agriculture research in sub‐Saharan Africa countries: a systematic map." Precision Agriculture Journal. 2021.
Haubek D, Mullie T, Kemoli A, Lindholm M, Gjørup H, Nørregaard M-LM, Johansson A. "Prevalence of JP2 and Non-JP2 Genotypes of Aggregatibacter actinomycetemcomitans and Oral Hygiene Practice of Kenyan Adolescents in Maasai Mara." Pathogens. 2021;2021, 10,488.(2021, 10,488.):2021, 10,488.
S A, GO O, E A, J K. "Profiles of vitamin D among patients with rheumatoid arthritis at the Kenyatta National Hospital." Af r ic a n J o u r n a l o f R h e u mat o l o g y. 2021;9(1):23-27. Abstractprofiles_of_vitamin_d_among_patients_with_ra_at_knh.pdf

Background: Rheumatoid Arthritis (RA)
is an autoimmune, chronic debilitating
condition of undetermined cause. It
affects numerous extra- articular organ
systems. Vitamin D is a steroid hormone
synthesized in the skin by the action of
ultraviolet B (UVB) irradiation. Active
vitamin D is important in the inhibition
of T cell proliferation and downregulation
of key inflammatory cytokines
responsible for the pathogenesis of RA.
There is growing evidence demonstrating
the association between vitamin D
insufficiency and higher incidence of RA
as well as increased severity of disease
and increased functional disability in RA
patients.
Objective: The purpose of this study
was to determine serum vitamin D levels
among patients with rheumatoid arthritis
at the Kenyatta National Hospital (KNH)
and its association with disease activity
and functional disability.
Design: This was a descriptive crosssectional
survey.
Methods: The study involved subjects
with RA at the Kenyatta National Hospital.
Consecutive sampling technique to
recruit patients with rheumatoid arthritis,
having met the 2010 American College
of Rheumatology/ European League
Against Rheumatism (ACR/EULAR)
classification criteria was selected. Ten
mls of peripheral blood was collected
from the recruited subjects to determine
serum vitamin D levels. Every participant
had their demographics, clinical history
and disease duration documented. Clinical
Disease Activity Index (CDAI) was used
to assess disease activity and severity. It
comprised of number of tender joint out
of 28 joints (T-28), number of swollen
joints out of 28 (S-28) global health
assessment score by both the physician
and the patient. level of disability was
determined by the standard Modified
Health Assessment Questionnaire
(MHAQ). Data analyzed was correlated
to determine their association with serum
vitamin D levels. SPSS version 21 was
used to analyze the data collected and this
entailed descriptive statistics, chi-square,
ANOVA and students’-test to compare
and correlate vitamin D levels with age,
duration of disease, CDAI score and
modified HAQ score in RA.
Results: Eighty one patients with a mean
age of 48.7 (SD 13.9), median of 48.0
(IQR 40.0-59.0) were evaluated. The
female to male ratio was 4:1. The mean
serum 25-VD concentration was 34.9ng/
ml (SD11.6). Thirty five participants
(43.2%) had insufficient vitamin D levels
(<30ng/ml), whereas 46 study participants
(56.8%) had sufficiency of vitamin D.
Majority of the patients 54 (67.5%) had
low disease activity. Fourteen subjects
17.5% had high disease activity and while
2.5% were on remission. Functional
disability was assessed using the modified
health assessment questionnaire. Thirty
eight participants (46.5%) demonstrated
no disability, 33.8% had mild disability
while 9% had severe disability.
Correlation between vitamin levels with
age, duration of disease, CDAI and HAQ
did not attain statistical significance.
Conclusion: Vitamin D insufficiency is
high among patients with rheumatoid
arthritis with no correlation with age,
duration of disease, functional disability
and disease activity.
Key words: Rheumatoid arthritis,
Vitamin D, Disease activity, Functional
disability, Cytokines
Introduction

S1 A, GO O, E3 A, J4 K. "Profiles of vitamin D among patients with rheumatoid arthritis at the Kenyatta National Hospital." Department of Clinical Medicine and Therapeutics, College of Health Sciences, University of Nairobi,. 2021;1(1):23-27.
Ngwili N, Johnson N, Wahome R, Githigia S, Roesel K, Thomas L. "A qualitative Assessment of the Context and Enabling Environment for the Control of Taenia solium Infections in Endemic Settings." PLOS Negl Trop Diseases. 2021;15(6. https://doi.org/10.1371/journal.pntd.0009470).
Harmsen H, Wangondu V, Mbau JS, J M, J M. "Randomized hotspot strategy is effective in countering bushmeat poaching by snaring." Biological conservation. 2021;253(108909).
Chemonges CC, Joshua N, Granai M, Lazzi S, Ndungu JR, Leoncini L. "A review of the sub-classification of lymph node biopsies reported as reactive lymphadenitis at Kenyatta National Hospital, Kenya." Int. J Pathol Clin Res. . 2021;7(1):120.
S.I.Akaranga, T.K.Musili, J.M.Karicha. "Secularization of Marriage Ritual Among the Ameru in Kenya." East African Journal of Traditions, Culture and Religion. 2021;3(2):52-59.
Jekayinoluwa T, Tripathi JN, Dugdale B, Obiero G, E M, Dale J, L T. "Transgenic Expression of dsRNA Targeting the Pentalonia nigronervosa acetylcholinesterase Gene in Banana and Plantain Reduces Aphid Populations." Plants.. 2021;10 (4)(613):1-18.
Simon PB, Joseph JO, Ochieng JW, Christian Keambou Tiambo, Getinet Mekuriaw Tarekegn, Machuka EM, Kabange D, Musale K, Ciza AM, Kizungu RV, Pelle R. "Typology, management and smallholder farmer-preferred traits for selection of indigenous goats (Capra hisrcus) in three agro-ecological zones in the Democratic Republic of Congo." Journal of Applied Animal Research. 2021;49(1):423-430.
P C, G L, Sangula A, J O, DP K, B H. "Understanding what shapes disease control: An historical analysis of foot-and-mouth disease in Kenya." Prev Vet Med. 2021;(PMID: 33735817).
Eric A, Elizaphan M, Rhoda G, Robert O, John K. "University Students' Perception on the Usefulness of Learning Management System Features in Promoting Self-Regulated Learning in Online Learning." International Journal of Education and Development using Information and Communication Technology. 2021;v17 (n1 ):45-64 . Abstract

Online learning has increasingly been adopted by most institutions of higher learning to facilitate teaching and learning as a continuum to the traditional face-to-face approach. Most of these institutions utilize Learning Management Systems which contain features that are intended to make students active participants not only by delivering learning resources to learners but also providing the environment for effective interaction in the learning process. Our examination of the literature reveals that there is limited empirical evidence that addresses how these features are being utilized by students in promoting Self-Regulated learning. To realize the usefulness of the features of Learning Management Systems in promoting Self-Regulated Learning, a structured survey was carried out among University students in Kenya. The findings reveal that the features of Learning Management Systems are underutilized by students. The qualitative results of the study illustrate that students face several challenges that obstruct them from being actively involved in online learning. There is lack of individualized feedback on students' learning habits, lack of instructor guidance, lack of interaction with course instructors, lack of peer interaction and lack of automation tools. This study provides insights for educators and researchers on the areas of focus that can be prioritized towards offering support to students in improving their Self-Regulated learning in online learning environments.

Rebecca Lynne C, Rikesh Panchal, Emmanuel, Michael G, Moses N, Nyangaya J, O M, J M, P K, A A, A R, M P, V J. "Volatile Organic Compound Composition of Urban Air in Nairobi Kenya and Lagos Nigeria.". 2021.
MK N, J D, M N, et al. "Why is There Low Morbidity and Mortality of COVID-19 in Africa." Am J Trop Med Hyg. 2021;10.4269/ajtmh.20-0474.
Odera S, Julius Oyugi, Kirui A, Aballa A, Noel Onyango, others. "Challenges Faced by House-Hold Contacts of Pulmonary Tuberculosis Patients in an Urban Setting in Nairobi, Kenya." Journal of Infectious Diseases & Case Reports. SRC/JIDSCR-165. DOI: doi. org/10.47363/JIDSCR/2021 (2). 2021;146:2-4. Abstract
n/a
Amwoka EM, Ambuko JL, Jesang HM, Owino WO. "Effectiveness of Selected Cold Chain Management Practices to Extend Shelf Life of Mango Fruit." Advances in Agriculture. 2021;2021. Abstract
n/a
Wang C, Jiang X, Sweeney WR, Hsu CW, Liu Y, Zhao G, Peng B, Zhang M, Jiang L, Stone DA, others. "Induced transparency by interference or polarization." Proceedings of the National Academy of Sciences. 2021;118. Abstract
n/a
MalariaGEN, Ahouidi A, Ali M, et al. "An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples." Wellcome Open Res.. 2021;6:42. Abstract

MalariaGEN is a data-sharing network that enables groups around the world to work together on the genomic epidemiology of malaria. Here we describe a new release of curated genome variation data on 7,000 Plasmodium falciparum samples from MalariaGEN partner studies in 28 malaria-endemic countries. High-quality genotype calls on 3 million single nucleotide polymorphisms (SNPs) and short indels were produced using a standardised analysis pipeline. Copy number variants associated with drug resistance and structural variants that cause failure of rapid diagnostic tests were also analysed. Almost all samples showed genetic evidence of resistance to at least one antimalarial drug, and some samples from Southeast Asia carried markers of resistance to six commonly-used drugs. Genes expressed during the mosquito stage of the parasite life-cycle are prominent among loci that show strong geographic differentiation. By continuing to enlarge this open data resource we aim to facilitate research into the evolutionary processes affecting malaria control and to accelerate development of the surveillance toolkit required for malaria elimination.

Zhang J, Peng B, Kim S, Monifi F, Jiang X, Li Y, Yu P, Liu L, Liu Y-xi, Alù A, others. "Optomechanical dissipative solitons." Nature. 2021;600:75-80. Abstract
n/a
Yumbya P, Ambuko J, Hutchinson M, Owino W, Juma J, Machuka E, Mutuku MJ. "Transcriptome analysis to elucidate hexanal's mode of action in preserving the post-harvest shelf life and quality of banana fruits (Musa acuminata)." Journal of Agriculture and Food Research. 2021;3:100114. Abstract
n/a
Jekayinoluwa T, Tripathi JN, Dugdale B, Obiero G, Muge E, Dale J, Tripathi L. "Transgenic Expression of dsRNA Targeting the Pentalonia nigronervosa acetylcholinesterase Gene in Banana and Plantain Reduces Aphid Populations." Plants. 2021;10:613. Abstract
n/a
2020
Naidoo K, Kempen JH, Gichuhi S, Braithwaite T, Casson RJ, Cicinelli MV, Das A, Flaxman SR, Jonas JB, Keeffe JE, Leasher J, Limburg H, Pesudovs K, Resnikoff S, Silvester AJ, Tahhan N, Taylor HR, Wong TY, Bourne RRA. "Prevalence and causes of vision loss in sub-Saharan Africa in 2015: magnitude, temporal trends and projections." Br J Ophthalmol. 2020. AbstractWebsite

Background: This study aimed to assess the prevalence and causes of vision loss in sub-Saharan Africa (SSA) in 2015, compared with prior years, and to estimate expected values for 2020.

Methods: A systematic review and meta-analysis assessed the prevalence of blindness (presenting distance visual acuity <3/60 in the better eye), moderate and severe vision impairment (MSVI; presenting distance visual acuity <6/18 but ≥3/60) and mild vision impairment (MVI; presenting distance visual acuity <6/12 and ≥6/18), and also near vision impairment (

Nanteza A, Obara I, Kasaija P, Mwega E, Kabi F, Salih DA, Njahira M, Joyce Njuguna, Odongo D, Bishop RP, Skilton RA, Ahmed J, Clausen P-H, Lubega GW. "Antigen gene and variable number tandem repeat (VNTR) diversity in Theileria parva parasites from Ankole cattle in south-western Uganda: Evidence for conservation in antigen gene sequences combined with extensive polymorphism at VNTR loci." Transbound Emerg Dis. 2020;67 Suppl 1:99-107. Abstract

Theileria parva is a tick-transmitted apicomplexan protozoan parasite that infects lymphocytes of cattle and African Cape buffalo (Syncerus caffer), causing a frequently fatal disease of cattle in eastern, central and southern Africa. A live vaccination procedure, known as infection and treatment method (ITM), the most frequently used version of which comprises the Muguga, Serengeti-transformed and Kiambu 5 stocks of T. parva, delivered as a trivalent cocktail, is generally effective. However, it does not always induce 100% protection against heterologous parasite challenge. Knowledge of the genetic diversity of T. parva in target cattle populations is therefore important prior to extensive vaccine deployment. This study investigated the extent of genetic diversity within T. parva field isolates derived from Ankole (Bos taurus) cattle in south-western Uganda using 14 variable number tandem repeat (VNTR) satellite loci and the sequences of two antigen-encoding genes that are targets of CD8+T-cell responses induced by ITM, designated Tp1 and Tp2. The findings revealed a T. parva prevalence of 51% confirming endemicity of the parasite in south-western Uganda. Cattle-derived T. parva VNTR genotypes revealed a high degree of polymorphism. However, all of the T. parva Tp1 and Tp2 alleles identified in this study have been reported previously, indicating that they are widespread geographically in East Africa and highly conserved.

Jekayinoluwa T, Tripathi JN, Obiero G, Muge E, Tripathi L. "Phytochemical Analysis and Establishment of Embryogenic Cell Suspension and -mediated Transformation for Farmer Preferred Cultivars of West African Plantain ( spp.)." Plants (Basel). 2020;9(6). Abstract

Banana and plantain are among the foremost staple food crops providing food and livelihood to over 500 million people in tropical countries. Despite the importance, their production is hampered due to several biotic and abiotic stresses. Plant tissue culture techniques such as somatic embryogenesis and genetic transformation offer a valuable tool for genetic improvement. Identification and quantification of phytochemicals found in banana and plantain are essential in optimizing in vitro activities for crop improvement. Total antioxidants, phenolics, flavonoids, and tannins were quantified in various explants obtained from the field, as well as in vitro plants of banana and plantain cultivars. The result showed genotypic variation in the phytochemicals of selected cultivars. The embryogenic cell suspensions were developed for three farmer-preferred plantain cultivars, Agbagba, Obino l'Ewai, and Orishele, using different MS and B5-based culture media. Both culture media supported the development of friable embryogenic calli (FEC), while MS culture media supported the proliferation of fine cell suspension in liquid culture media. The percentage of FEC generated for Agbagba, Obino l'Ewai, and Orishele were 22 ± 24%, 13 ± 28%, and 9 ± 16%, respectively. Cell suspensions produced from FECs were successfully transformed by -mediated transformation with reporter gene constructs and regenerated into whole plants.

Koyaweda GW, Ongus JR, Machuka E, Juma J, Macharia R, Komas NP, Pelle R. "Detection of circulating hepatitis B virus immune escape and polymerase mutants among HBV-positive patients attending Institut Pasteur de Bangui, Central African Republic." Int J Infect Dis. 2020;90:138-144. Abstract

Previous studies in the Central African Republic (CAR) have reported the presence of hepatitis B virus (HBV) recombinant genotype E/D and a suspicion of immune escape mutants (IEMs), without further investigation into their impact on prevention and diagnosis. Consequently, this study investigated HBV mutations among hepatitis B surface antigen (HBsAg)-positive patients attending Institut Pasteur de Bangui in the CAR.

Mwamuye MM, Obara I, Elati K, Odongo D, Bakheit MA, Jongejan F, Nijhof AM. "Unique Mitochondrial Single Nucleotide Polymorphisms Demonstrate Resolution Potential to Discriminate Vaccine and Buffalo-Derived Strains." Life (Basel). 2020;10(12). Abstract

Distinct pathogenic and epidemiological features underlie different strains resulting in different clinical manifestations of East Coast Fever and Corridor Disease in susceptible cattle. Unclear delineation of these strains limits the control of these diseases in endemic areas. Hence, an accurate characterization of strains can improve the treatment and prevention approaches as well as investigate their origin. Here, we describe a set of single nucleotide polymorphisms (SNPs) based on 13 near-complete mitogenomes of strains originating from East and Southern Africa, including the live vaccine stock strains. We identified 11 SNPs that are non-preferentially distributed within the coding and non-coding regions, all of which are synonymous except for two within the gene of buffalo-derived strains. Our analysis ascertains haplotype-specific mutations that segregate the different vaccine and the buffalo-derived strains except Muguga and Serengeti-transformed strains suggesting a shared lineage between the latter two vaccine strains. Phylogenetic analyses including the mitogenomes of other species: , , and , with the latter two sequenced in this study for the first time, were congruent with nuclear-encoded genes. Importantly, we describe seven haplotypes characterized by synonymous SNPs and parsimony-informative characters with the other three transforming species mitogenomes. We anticipate that tracking mitochondrial haplotypes from this study will provide insight into the parasite's epidemiological dynamics and underpin current control efforts.

Oladapo OT, Vogel JP, Piaggio G, et al. "Antenatal Dexamethasone for Early Preterm Birth in Low-Resource Countries." N Engl J Med. 2020;383(26):2514-2525. Abstract

The safety and efficacy of antenatal glucocorticoids in women in low-resource countries who are at risk for preterm birth are uncertain.

Oladapo OT, Vogel JP, Piaggio G, et al. "Antenatal Dexamethasone for Early Preterm Birth in Low-Resource Countries." N Engl J Med. 2020;383(26):2514-2525. Abstract

The safety and efficacy of antenatal glucocorticoids in women in low-resource countries who are at risk for preterm birth are uncertain.

of Joint Report Kenya National Bureau of Statistics(KNBS) UN. Inequality trend and Diagnostics in Kenya. Nairobi: University of Nairobi and KNBS; 2020.
Joselyne NM, Waweru M, Gitau AN, Alphonse U, Patrick M. " Evaluating Anaerobic Digestion Technology in Reducing the Quantity of Solid Waste: Case of Kigali Dumpsite. ." Journal of Geoscience and Environment Protection. 2020;8(ISSN: 2327-4344):204-220.
S.O O, J.N M, R. T, M K. "African Images in Kithaka wa Mberia's Poetry." Asian Journal of African Studies, Institute of African Studies,Hankuk University of Foreign Studies. 2020;49(August 2020):3-28.
JessicaOsanya, I.Adam R, Otieno DJ, Nyikal R, Jaleta M. "An analysis of the respective contributions of husband and wife in farming households in Kenya to decisions regarding the use of income: A multinomial logit approach." Women's Studies International Forum. 2020;83. AbstractWebsite

This paper analyzes the socio-economic characteristics of households that affect husbands and wives' contributions to decisions regarding the use of income from crop and livestock sales in Kenya. Using a sample of 276 households, we apply a multinomial logit model to assess factors affecting decision-making. Results show that husbands make most decisions concerning agriculture, while wives mainly decide on daily household expenditure. Higher education levels were found to increase women's involvement in decision-making on income use. Group membership had a positive effect on joint decision-making on income use. The study recommends improving women's access to education, which will improve their access to productive resources, hence their decision-making power. Providing incentives for members of agricultural groups can provide avenues for learning. Gender-transformative approaches that empower women and sensitize men to allow space for women to engage in decision-making, can have an impact in improving the decision-making capacity of women in households.

Joseph Muiruri, Wahome R, Karatu K. "Assessment of methods practiced in the disposal of solid waste in Eastleigh Nairobi County, Kenya [J]." AIMS Environmental Science. 2020;7(5):434-448.
Ochiba N.K,.A. A’oD, J.O. O. "Assessment of selected heavy metals levels in borehole water in Ongata Rongai, Kajiado County, Kenya." Journal of Science and Technology. 2020;6:9-17.
James. N. Mugo, Nancy N. Karanja, Gachene CS, Klaus Dittert, Nyawade SO, Schulte-Geldermann E. "Assessment of soil fertility and potato crop nutrient status in Central and Eastern Highlands of Kenya." Nature research. 2020.
MO F, M ET, NM A, OB A-B, RJ S, JL C, JI V, BO G, R A, A K, A V, CA F. "Association between early childhood caries and poverty in low and middle-income countries." BMC Oral health. 2020;2020; 20:8(2020; 20:8):2020; 20:8.
N A, NM A, MO F, Y K, JI V, OB A-B, SZ M, S A, H H, S B, DA M, A R, I K, M M, M R, V P, S C, Y C, E J, JL C, K N, A S, G G, A P, P P, D M, J K, MM A, A A, MA D, M N, I H, MM A, AP V, A I, AM K, ME T. "Behavior change due to COVID-19 among dental academics - The theory of planned behavior: stresses, worries, training, and pandemic severity." PLoS ONE. 2020;15(9): e0239961(15(9): e0239961):15(9): e0239961.
Jeneby F, Badrus A, Taib H, Alluso A, Odiemo L, Otanga H. "Best practices in reaching ‘hidden’ populations and harm reduction service provision.". In: The Impact of Global Drug Policy on Women: Shifting the Needle. New York: Emerald Publishing Company; 2020.
Jane Ireri, Pokhariyal G, Moindi S. "Chemostat Model with Periodic Nutrient Input Described by Fourier Series." Asian Research Journal of Mathematics. 2020;16(8):16-27. AbstractWebsite

In this paper we present a periodic Chemostat model of two species competing for a single nutrient available in limiting supply. The nutrient input is varied periodically using a Fourier series function to take into account the changing patterns as seasons vary. We show both analytically and numerically that varying the nutrient input using a Fourier Series function results in a better model to describe coexistence of species in natural environments.

Richard N. Onwonga, Ruth C. Sitienei, Joyce J. Lelei, Kamoni P. "Complementary Effects of Legume Integration and Fertilizer application on Soil Moisture and Long-Term Carbon Stocks in Maize Systems of Kabete Sub-County, Kenya." Tropical and Subtropical Agroecosystems. 2020.
M G, L M, AU A, MC S, H R, V M, N O, J N, OA A, I M, S M, W W, M B, PP P, L Q-M, F F, S L, Leoncini L, T M. "Correction: Immune landscape in Burkitt lymphoma reveals M2-macrophage polarization and correlation between PD-L1 expression and non-canonical EBV latency program. ." Infect Agent & Cancer . 2020;15(39):doi:10.1186/s13027-020-00304-9.
Jane Ireri, Pokhariyal G, Moindi S. "Delayed Nutrient Conversion for a Single Species Periodic Chemostat." Journal of Scientific Research and Reports. 2020;26(5):1-9. AbstractWebsite

In this paper we analyze a Chemostat model with periodic nutrient input modelled using Fourier series and incorporate delays in nutrient conversion. We show that both periodicity and delays have complementing influence in the long term behaviour of the species. Numerical results show that periodicity has bigger influence on species density variations for delays below the Hopf Bifurcation point, while for delays above the Bifurcation point,the delay effect is more influential.

Lutta AI, Wasonga OV, Robinson LW, Nyangito MM, Jason Sircely. "Determinants of livestock market participation among pastoral communities of Tana River County, Kenya." Environment, Development and Sustainability. 2020.
Sola L, Levin NW, Johnson DW, Pecoits-Filho R, Aljubori HM, Chen Y, Claus S, Collins A, Cullis B, Feehally J, Harden PN, Hassan MH, Ibhais F, Kalantar-Zadeh K, Levin A, Saleh A, Schneditz D, Tchokhonelidze I, Kazancioglu RT, Twahir A, Walker R, Were AJO, Yu X, Finkelstein FO. "Development of a framework for minimum and optimal safety and quality standards for hemodialysis and peritoneal dialysis." Kidney International Supplements. 2020.
U B, M M, J M, Mwang’ombe, S G. "Disease surveillance and farmers’ knowledge of Brachiaria (Syn. Urochloa) grass diseases in Rwanda." African Journal of Range & Forage Science. 2020;. https://doi.org/10.2989/10220119.2020.1810774.
MO F, ME T, B G, RJ S, J C, OB A-B, A K, AC MD, V P, M R. "An Ecological Study of the Association Between Environmental indicators and early childhood caries." BMC Res Notes. 2020;2020, 13:474.(2020, 13:474.):2020, 13:474.
Alphayo I. Lutta, Lance W. Robinson, Oliver V. Wasonga, Ruto E, Jason Sircely, Nyangito MM. "Economic valuation of grazing management practices: discrete choice modeling in pastoral systems of Kenya." Environmental Planning and Management. 2020;63(2).
Marete GN, Kanja LW, Mbaria JM, Okumu MO, Ateku PA, Korhonen H, Joutsjoki V. "Effects of the Use of Good Agricultural Practices on Aflatoxin Levels in Maize Grown in Nandi County, Kenya." Sci. 2020;2, 26.
Marete GN, Kanja LW, Mbaria JM, Okumu MO, Ateku PA, Korhonen H, Joutsjoki V. "Effects of the Use of Good Agricultural Practices on Aflatoxin Levels in Maize Grown in Nandi County, Kenya." Sci. 2020;2, 85.
Nkunu Z, M GP, J.G. K. "Electrocatalytic reduction and characterization of Tetrachlorvinphos in acetonitrile-water (1:1) media in presence of cyanocobalamin." Africa Journal of Physical Sciences. 2020;4:xxxx. Abstractabstract.pdfAfrica Journal of Physical Sciences

Abstract

This work investigates a possible electrocatalytic degradation of tetrachlorvinphos pesticide in acetonitrile-water media using cyanocobalamin as the catalyst. The catalyst and its derivatives are employed in some organic synthesis due to their ability to form and selectively cleave Co-C bonds. There is inadequate data from previous related works. This study explores possible electrocatalytic route for degradation of tetrachlorvinphos using the catalyst at temperature of 24 ± 1° by cyclic voltammetry method. Tetrachlorvinphos exhibited two consecutive reduction peaks at ~-0.710 ± 0.004 V and ~ -1.096 ± 0.029 V Versus Ag/AgCl. The second reduction peak registered a diffusion coefficient value of 3.68 x 10-5 cm2s-1 and current density of be 5.83 x 10-5 A/cm2. The reduction potential for tetrachlorvinphos in presence of cyanocobalamin was observed to be -0.923 ± 0.03 V versus Ag/AgCl. The diffusion coefficient and current density value was reported at 3.37 x 10-5 cm2s-1 and 2.56 X 10-5 A/cm2 respectively for an electro-reduction process. This implies that, catalytic reduction of the pesticide occurred at a significantly lower potential compared to direct reduction. The over potential saving of about 0.168 V is an indication of the catalyst efficiency on the pesticide degradation.

G M, G MI, J M. "End-of-Life Care Education Needs OF Nurses: A Cross-Sectional Study." Annals of Nursing and Practice. 2020;7(1).
D O, J.N O, A.S O, A.A S. "Evaluation of the physical properties of leathers tanned with Plectranthus barbatus Andrews extracts." African Journal of Biotechnology. 2020;19(3):137-141.
Gichure M, J O, R W, P G. "Factors associated with level of income derived from working donkeys for smallholder farmers in the central highlands of Kenya." East African Journal of Science, Technology and Innovation . 2020;1(4).
Astère Bararyenya, Bode A. Olukolu, Phinehas Tukamuhabwa, Wolfgang J. Grüneberg, Ekaya W, Jan Low, Mildred Ochwo-Ssemakula TOL. "Genome-wide association study identified candidate genes controlling continuous storage root formation and bulking in hexaploid sweetpotato." BMC Plant Biology . 2020;20(1):1-16.
Chebii WK, John M, Karatu K. "The governance of traditional medicine and herbal remedies in the selected local markets of Western Kenya." Journal of Ethnobiology and Ethnomedicine . 2020;39(16).
Jane Ireri, Pokhariyal G, Moindi S. "Hopf Bifurcation Analysis for a Two Species Periodic Chemostat Model with Discrete Delays." Journal of Advances in Mathematics and Computer Science. 2020;35(3):93-105. AbstractWebsite

In this paper we analyze a Chemostat model of two species competing for a single limiting nutrient input varied periodically using a Fourier series with discrete delays. To understand global aspects of the dynamics we use an extension of the Hopf bifurcation theorem, a method that rigorously establishes existence of a periodic solution. We show that the interior equilibrium point changes its stability and due to the delay parameter it undergoes a Hopf bifurcation.
Numerical results shows that coexistence is possible when delays are introduced and Fourier series produces the required seasonal variations. We also show that for small delays periodic variations of nutrients has more influence on species density variations than the delay.

M G, L M, AU A, MC S, H R, V M, N O, J N, OA A, I M, S M, W W, M B, PP P, L Q-M, F F, S L, Leoncini L, T M. "Immune landscape in Burkitt lymphoma reveals M2-macrophage polarization and correlation between PD-L1 expression and non-canonical EBV latency program. ." Infectious Agents & Cancer . 2020;15(28).
Calistus N Ngonghala, Wairimu J, Jesse Adamski, Desai H. "IMPACT OF ADAPTIVE MOSQUITO BEHAVIOR AND INSECTICIDE-TREATED NETS ON MALARIA PREVALENCE." Journal of Biological Systems. 2020;28(2):515-542. AbstractWebsite

Malaria prevalence in sub-Saharan Africa remains high. Kenya for example, records about 3.5 million new cases and 11 thousand deaths each year.1 Most of these cases and deaths are among children under five. The main control method in malaria endemic regions has been through the use of insecticide-treated nets (ITNs). Although this approach has been fairly successful, the gains are threatened by mosquito-resistance to pyrethroids (insecticides on nets), physical and chemical degradation of ITNs that reduce their efficacy, inconsistent and improper use by humans, etc. We present a model to investigate the effects of ITN use and mosquito-resistance and adaptation to pyrethroids used to treat bed nets on malaria prevalence and control in malaria endemic regions. The model captures the development and loss of resistance to insecticides, the effects of ITN use on malaria control in a setting where proper and consistent use is not …

S. S, Gitau G.K., J. VL, C. M, P. K. "Impact of calf feeding practices on calf growth and health in smallholder dairy farms in Nyeri County, Kenya." East African Journal of Science, Technology, and Innovation. 2020;1(3):2707-0425.
E L, M K, S S, FH R, Kinuthia J, L S, W J, H A, A K, F E, John-Stewart, Fredricks DN, McClelland S. "Impact of preconception vaginal microbiota on women’s risk of spontaneous preterm birth: Protocol for a prospective case-cohort study." BMJ Open J. 2020;2020; 10:e035186(2020; 10:e035186):2020; 10:e035186.
Mucai J.M., Awino Z.B., Aosa E., J.N. M. "The Influence of Tacit Knowledge on Competitive Advantage: Learning from ICT Service Providers in Nairobi." Archives of Business Research,. 2020;6(7).

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