Mwangi J.W. Guantai A.N., Muriuki G., Kwande W.Constituents of the essential oil of ocimum fischeri guerke. Kenya J. Sci series (B) 9:119-121 1988

Citation:
N PROFGUANTAIA. "Mwangi J.W. Guantai A.N., Muriuki G., Kwande W.Constituents of the essential oil of ocimum fischeri guerke. Kenya J. Sci series (B) 9:119-121 1988.". In: Kenya J. Sci series (B) 9:119-121 1988. Ivan Addae-Mensah,t Rahab Munenge and Anastasia N. Guantai; 1988.

Abstract:

Cardiovascular activities of nitidine chloride from Zanthoxylunt chalybeum have been compared with those of 9-methoxychelerythrine. Whereas nitidinc chloride was found to show significant hypotensive activity in rabbits, 9-methoxychelerythrine chloride showed no hypotensive activity. The effect of nitidine chloride on isolated rabbit heart was also compared with those of adrenaline and acetylcholine. 9-Methoxychelerythrine, which has hitherto been regarded as an artefact formed by recrystallization of chelerythrine base from methanol, has been shown in this work to be a true natural constituent of Zanthoxylum chalybeum. Keywords: 9-inethoxychelerythrine; nitidine chloride; cardiovascular properties; hypotensive effect; Zanthoxylum chalybeum.

Notes:

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