Increased risk of infection with human immunodeficiency virus type 1 among uncircumcised men presenting with genital ulcer disease in Kenya. Tyndall-MW; Ronald AR; Agoki-E; Malisa-W; Bwayo JJ; Ndinya-Achola-JO; Moses-S; Plummer-FA. Clin-Infect-Dis. 1996 S

Citation:
JOAB PROFBWAYOJOB. "Increased risk of infection with human immunodeficiency virus type 1 among uncircumcised men presenting with genital ulcer disease in Kenya. Tyndall-MW; Ronald AR; Agoki-E; Malisa-W; Bwayo JJ; Ndinya-Achola-JO; Moses-S; Plummer-FA. Clin-Infect-Dis. 1996 S.". In: Clin-Infect-Dis. 1996 Sep; 23(3): 449-53. Asian Economic and Social Society; 1996.

Abstract:

The factors responsible for the explosive spread of human immunodeficiency virus type 1 (HIV-1) in sub-Saharan Africa continue to be identified and debated. One of the most controversial factors has been male circumcision. This cross-sectional study was conducted to measure the association between circumcision status and infection with HIV-1 among men with genital ulcer disease. Eight hundred and ten men participated in the study, of whom 190 (23%) were HIV-1-positive. A logistic regression model adjusted for behavioral and historical showed that HIV-1 positivity was independently associated with being uncircumcised (adjusted odds ratio [OR], 4.8; 95% confidence interval [CI], 3.3-7.2) and with a history of urethral discharge (adjusted OR, 2.0; 95% CI, 1.4-2.8). This association could not be explained by measures of sexual exposure to HIV-1 among this population. Male circumcision should be considered as an intervention strategy for AIDS control.

Notes:

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